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Question: Car is hesitant to accelerate

Maybe I can get some other opinions about this issue..
When I try to accelerate a bit more after reaching a hwy speed, my engine seems to be "skipping" or "hesitant" to accelerate more. It eventually does it if i let off the accelerator a bit and try again. It does not do it when I am at a stop and accelerate the car. Only after I am already driving and trying to speed up a little bit.
Someone said it might be a misfire with the spark plugs, but they were replaced 20K ago.
The fuel pump, filter, and screen was replaced 6 months ago. The mechanic said the filter was really dirty, but I just had him replace the whole pump system. (the pump worked, the clogged filter just caused the breakdown) But it seems like it is happening all over again.
Transmission shifts perfectly and everything else works great. It idols very smoothly and accelerates fine from a stopping point up to speed. I only have 105K on the car and it has been very well taken care of (one owner).
What do you suggest I do next?
If I should try getting the fuel system cleaned out (i don't know if they did it when the pump was replaced) what is the best procedure for them to do? Or would a simple bottle of fuel cleaner and premium gas clear it up?